Side Effects of Paxil

Paxil, aka Paroxetine, whose parent manufacturer is GSK (GlaxoSmithKline), is, according to the FDA, a medication with a number of fairly serious side effects.

The irony of this is that Paxil is intended for the treatment of depressions and its various forms, including obsessive-compulsive disorder, panic and less severe depressive states, such as social anxiety and generalized anxiety disorder.

As one often sees with a drug such as this (that is, one that treats behavioral or motivational dysfunction),the side effects of Paxil can, in some few cases, be far more serious than the disorder the medication was intended to alleviate.

No far-reaching ban of Paxil has been called for, however, as in the case of other anti-depressants, and probably none will be since the FDA cautions health providers to give the fullest explanation possible, to their patients, of Paxil’s potential dangers.

The side effects of Paxil are not extensive nor severe but they can be serious.  Mitigating this is the drug’s efficacy, comparable to most other tricyclic antidepressants (named for their tri-cellular chemical construction).   It is, as the FDA discovered and Wikipedia announced, a nominally safe drug for most patients with these disorders; its side effects are limited to less than ¼ of the patients treated, although these effects can be problematic.

One of the Side Effects of Paxil is Sexual Dysfunction?

The most frequently experienced of the side effects of Paxil is sexual dysfunction, a condition that is both common and, in some cases, temporal.  It is far from certain that Paxil is the root cause of this disorder, since it is entirely possible that a sexually dysfunctional individual would become depressed and seek out a medication—such as Paxil.

This remains, however, the most prevalent of the paxil side effects; there was also a recent study in which pregnant animals, given the drug, experienced birth defects (see also topirimate birth defects) in their offspring, including heart defects that led to fetal death, as well as miscarriages.   As one researcher commented, a patient suffering from this disorder, confronted with these possible side effects, would be far more depressed than when he first undertook to include the medication in his treatment.

Other, less severe side effects include nausea, somnolence, insomnia, dizziness, constipation and tremors.   These took place in varying degrees among patients, from 26% occurrence (nausea) to less than 8% (tremors).  There is also the possibility of such conditions as high blood pressure, headache, weight gain, memory impairment and the numb/tingling of the skin (aka paresthesia).   The possibility exists of suicidal tendencies coming to the fore, as well as violent anxiety and dangerous impulses.

Paxil, as most researchers noted, remains an effective drug that nonetheless should be held at arm’s length, so to speak, for those prone to its more harmful side effects of paxil.

If you have any concerns or issues about Paxil’s side effects, consult your health professional.

http://www.fda.gov/downloads/Drugs/DrugSafety/ucm088676.pdf
http://en.wikipedia.org/wiki/Paroxetine
http://www.gsk.com/products/prescription-medicines/paxil.htm