Paroxetine Side Effects

Paroxetine, also known as Paxil (parent company GSK, GlaxoSmithKline), is a somewhat problematic drug in that the FDA  warnings, designed to preserve the safety of a patient, list, in many areas, precisely the problems the drug is intended to alleviate.

In one of the serious ironies of pharmaceuticals that are more frequent than one might imagine, Paroxetine side effects replicates some of the symptoms that the drug, effective for many, is intended to help.

Paroxetine first appeared in 1992 as a product of SmithKline Beecham, aka GlaxoSmithKline Pharmaceuticals. It is intended to treat depression in its more serious forms: major depression, obsessive-compulsive disorder and panic disorder.

In less frequent dosages, and dosages with reduced milligram content, the drug is used for social anxiety and generalized anxiety disorder.  Its effectiveness has never been under consideration, since the efficacy of the drug is largely unquestioned by the medical community.

Sexual Dysfunction- Serious Paroxetine Side Effects

However, as the FDA reminds its health providers, there are truly serious Paroxetine side effects to consider, so much so that doctors et al. are required to inform patients fully of the difficulties.

The most prevalent among these is sexual dysfunction, which alarmingly can last months or years beyond the point at which the intake of the drug is suspended and the system cleared.(read about side effects of paxil)   There is also a smaller chance of insomnia, somnolence, constipation and tremors (the least prevalent, suffered by 8% of the patients treated).

Far more problematic are those side effects as the FDA warns patients about, indicating the admittedly rare cases where Paroxetine side effects cause suicidal thoughts or actions (these are most prevalent in children and young adults, beginning within months of the onset of the treatments).

Depression and changes in mood, behavior and actions have been noted by some.  Again, patients have noted the irony of an anti-depressant that depresses them.

More serious still are the more exceptionally rare, but nonetheless FDA documented, side effects such as Serotonin Syndrome (which includes hallucinations, agitation and even possible coma).  As is always possible with any drug, there may be severe allergic reactions such as shortness of breath, swelling and rash.

There have been instances of abnormal bleeding, seizures, and manic episodes.  Many patients experience changes in weight and appetite.

Despite all this, Paxil remains “at large” as a frequently used drug, since it has far more effective uses than it does potentially dangerous side effects.  But it is a drug to keep under careful watch, and the FDA requirements that health providers educate their patients are well considered.

Consult a medical professional if you need further information about Paroxetine.

http://en.wikipedia.org/wiki/Paroxetine#Side_effects
http://www.fda.gov/downloads/Drugs/DrugSafety/ucm088676.pdf
http://www.gsk.com/media/paroxetine.htm